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It has been demonstrated that the number of GIP-producing cells, GIP content, and Pdx1 expression in GIP-producing cells increase in aged mice, while acquired Pdx1 knockdown using an intestine-specific gene transfer (iGT) technique decreases GIP gene expression and GIP content in GIP-producing cells and ameliorates GIP secretion after oral glucose loading
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Scientific Trajectory: On the science side, the GLP-1 wars have accelerated innovation
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